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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKD1
All Species:
26.06
Human Site:
S237
Identified Species:
57.33
UniProt:
Q15139
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15139
NP_002733.2
912
101704
S237
P
L
L
Q
K
S
P
S
E
S
F
I
G
R
E
Chimpanzee
Pan troglodytes
XP_001170806
912
101668
S237
P
L
L
Q
K
S
P
S
E
S
F
I
G
R
E
Rhesus Macaque
Macaca mulatta
XP_001114639
912
101836
S237
P
L
L
Q
K
S
P
S
E
S
F
I
G
R
E
Dog
Lupus familis
XP_851386
884
99023
S221
G
R
E
K
R
S
N
S
Q
S
Y
I
G
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q62101
918
102049
S243
G
F
E
Q
K
S
P
S
E
S
F
I
G
R
E
Rat
Rattus norvegicus
Q9WTQ1
918
102025
S243
G
F
E
Q
K
S
P
S
E
S
F
I
G
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512992
948
106688
S273
S
F
E
Q
K
S
P
S
E
S
F
I
G
R
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685219
878
98838
S215
P
G
R
G
R
S
N
S
Q
S
Y
I
G
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61267
476
54243
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45818
1070
120565
A412
C
L
E
A
L
D
A
A
R
P
S
S
T
L
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39009
513
58614
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.9
92
N.A.
92.5
93.1
N.A.
81.3
N.A.
N.A.
80.1
N.A.
20.1
N.A.
43.7
N.A.
Protein Similarity:
100
99.5
99.3
93.9
N.A.
95
95.4
N.A.
86.3
N.A.
N.A.
86.7
N.A.
32
N.A.
56.2
N.A.
P-Site Identity:
100
100
100
40
N.A.
80
80
N.A.
80
N.A.
N.A.
46.6
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
66.6
N.A.
80
80
N.A.
80
N.A.
N.A.
66.6
N.A.
0
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
34.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
10
0
0
0
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
46
0
0
0
0
0
55
0
0
0
0
0
55
% E
% Phe:
0
28
0
0
0
0
0
0
0
0
55
0
0
0
0
% F
% Gly:
28
10
0
10
0
0
0
0
0
0
0
0
73
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
73
0
0
0
% I
% Lys:
0
0
0
10
55
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
37
28
0
10
0
0
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% N
% Pro:
37
0
0
0
0
0
55
0
0
10
0
0
0
0
19
% P
% Gln:
0
0
0
55
0
0
0
0
19
0
0
0
0
0
0
% Q
% Arg:
0
10
10
0
19
0
0
0
10
0
0
0
0
73
0
% R
% Ser:
10
0
0
0
0
73
0
73
0
73
10
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _